Zhongke Runxin (Suzhou) Biotechnology Co., Ltd
Sales & Support:
 |
| Place of Origin: | China |
| Brand Name: | NUGLY |
| Certification: | FDA,ISO9001,ISO22000,FSSC22000 |
| Model Number: | NUGLY CK |
| Minimum Order Quantity: | 1mg |
|---|---|
| Price: | FOB Shanghai USD150/100g |
| Packaging Details: | 100g/bag |
| Delivery Time: | 10-20 work days |
| Payment Terms: | T/T,PAYPAL |
| Supply Ability: | 1ton/year |
| Product: | Organic Ginseng Root 90% Ginsenoside CK Compound K For Anti-Cancer Functuonal Raw Material | Functions: | Anti-Inflammatory |
|---|---|---|---|
| Usage Method: | Medical Excipients | Suitable People: | Inflammatory Patients |
| Color: | White | Grade: | Medical Grade |
| Storage: | Dry And Shade | Water Solubility: | Water Soluble |
| Shelf Life: | 24 Months | CAS No.: | 39262-14-1 |
| Specification: | Purity More Than 80% | Molecular Weight: | 622.873 |
| Source: | Ginseng Extract, Total Saponins Of Ginseng | Molecular Formula: | C36H62O8 |
| Density: | 1.05-1.1 |
High Purity Hundred Year Old Ginsenoside CK Medicinal Excipient
【Biological activity】
Ginsenoside C-K is a bacterial metabolite of Ginsenoside Rb1.
Ginsenoside C-K exerts anti-inflammatory effects by inhibiting inducible nitric oxide synthase (iNOS) and COX-2.
In human liver microsomes, Ginsenoside C-K inhibits CYP2C9 and CYP2A6 activity with IC50 values of 32.0 ± 3.6 μ M and 63.6 ± 4.2 μ M, respectively.
【High Purity Hundred Year Old Ginsenoside CK Medicinal Excipient】
| Appearance | White powder |
| Other Name | Medical grade Compound K |
| Applicable objects | Inflammatory Patients |
| Product form | Powder |
| Purity | 80% |
| Deacetylation degree | >90% |
| Viscosity (5%) | <10cps |
| Molecular weight | Around 600DA |
| loss on drying | <10% |
| residue on ignition | <1% |
| insoluble | <1% |
| pb | <2ppm |
| As | <1ppm |
| total plate count | <1000 cfu/g |
| mole and yeast | <25 cfu/g |
| E. coli | Negative |
| particle size | >80 mesh |
【In vitro research Of High Purity Hundred Year Old Ginsenoside CK Medicinal Excipient】
Inflammatory response plays a crucial role in maintaining liver homeostasis; Therefore, the levels of inflammatory factors such as IL-1 β, IL-6, and TNF - α are the top priority.
Experimental data showed that the 40mg/kg ginsenoside CK treatment group reduced the levels of TNF - α, IL-6, and IL-1 β by 16.4%, 16.7%, and 26.2%, respectively, compared to the mouse hepatitis model induced by ConA. This indicates that ginsenoside CK effectively reduces the secretion of pro-inflammatory factors TNF - α, IL-6, and IL-1 β, achieving anti-inflammatory effects.
Contact Person: Mr. Zhang
Tel: 86-13814814326
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