Food grade chitosan oligosaccharide powder liver detox ingredient factory supply

Chitosan oligosaccharide (COS) for Liver Protection | English Product Description

1. Physicochemical Properties

1. Appearance: Off-white fine powder, almost odorless, slight natural seafood aroma, free of insoluble residue.
2. Molecular index: Average molecular weight 300–1600 Da, DP 2–10; Deacetylation ≥92%, abundant free cationic amino groups as core active structure for liver-target binding and free radical scavenging.
3. Solubility: Fully soluble in neutral aqueous solution (pH5.0–7.0); insoluble in ethanol and organic solvents, superior water solubility vs high-molecular chitosan.
4. Quality specification: COS purity ≥90%(dry basis), moisture ≤9.0%, ash ≤1.0%; thermostable below 115℃, mildly hygroscopic, require sealed cool dry storage.
5. Absorption feature: Small-molecule oligomer can be rapidly absorbed through intestinal epithelium into blood circulation to reach liver tissue and exert hepatoprotective effects.

2. Hepatoprotective Mechanism & Test Data(Antioxidation,Hepatic anti-inflammation,Anti-fatty liver,Anti-fibrosis)

2.1 Scavenge hepatic free radicals & relieve oxidative liver injury

Animal test data: After continuous oral administration for 28 days on alcohol-induced liver injury model, hepatic MDA level drops by 47%, liver SOD & GSH-Px antioxidant enzyme activity rises by 52% and 43% separately vs control group.

 

2.2 Reduce liver inflammation & lower ALT/AST liver enzymes

Test data: For chemical-induced acute liver damage subjects, continuous COS supplementation reduces serum ALT by 39% and AST by 35% after 14 days administration.

 

2.3 Improve non-alcoholic fatty liver & regulate hepatic lipid metabolism

High-fat feeding model data: Long-term COS intake reduces hepatic triglyceride accumulation by 41%, effectively alleviate mild to moderate fatty liver lesions.

 

2.4 Inhibit early hepatic fibrosis development

In-vivo trial: Hepatic collagen content decreases by 32% after continuous 30-day COS intervention on fibrosis model mice.

 

2.5 Regulate gut-liver axis (Core synergy advantage of COS)

Flora test: Daily COS intake improves intestinal beneficial bacteria quantity by over 1.6 log CFU/g, lowers blood endotoxin concentration by 50%+.

 

3. Product Summary

Application

1. B2B Bulk Raw Material: Core functional raw material for liver detox capsules, fatty liver care compound powder, hangover liver-protect drinks, pet liver health feed additives; complete COA, SDS and third-party inspection reports for global bulk wholesale and OEM formula customization.
2. B2C Finished Supplement Formula: Premium natural marine-source liver care ingredient for long-term drinkers, overtime workers, sub-health crowd with abnormal liver index and mild fatty liver population for daily liver maintenance.
    
   As a novel multifunctional hepatoprotective raw material combining gut regulation and liver protection, COS is a high-growth niche ingredient in global liver health supplement track.
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